Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells

Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells

Glioblastoma (GBM) is an aggressive tumor of the brain, with an average post-diagnosis survival of 15 months. GBM stem cells (GBMSC) resist the standard-of-care therapy, temozolomide, and are considered a major contributor to tumor resistance. Mammalian target of rapamycin Complex 1 (mTORC1) regulat...

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Main Authors: Jose A. Sandoval (Author), Alexey Tomilov (Author), Sandipan Datta (Author), Sonia Allen (Author), Robert O'Donnell (Author), Thomas Sears (Author), Kevin Woolard (Author), Dmytro Kovalskyy (Author), James M. Angelastro (Author), Gino Cortopassi (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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