Development and validation of an Onchocerca ochengi adult male worm gerbil model for macrofilaricidal drug screening.

• Main Authors: Fidelis Cho-Ngwa (Author), Glory Enjong Mbah (Author), Rene Bilingwe Ayiseh (Author), Emmanuel Menang Ndi (Author), Elvis Monya (Author), Irene Memeh Tumanjong (Author), Evans Ngandung Mainsah (Author), Judy Sakanari (Author), Sara Lustigman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Onchocerciasis currently afflicts an estimated 15 million people and is the second leading infectious cause of blindness world-wide. The development of a macrofilaricide to cure the disease has been hindered by the lack of appropriate small laboratory animal models. Th...