New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia

• मुख्य लेखकों: Ahmed K. Hamdy (लेखक), Takashi Sakamoto (लेखक), Tsugumasa Toma (लेखक), Masaharu Sakamoto (लेखक), Mohammed A. S. Abourehab (लेखक), Masami Otsuka (लेखक), Mikako Fujita (लेखक), Hiroshi Tateishi (लेखक), Mohamed O. Radwan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different bio-pertinent activities, especially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin a...