New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia

• Үндсэн зохиолчид: Ahmed K. Hamdy (Зохиогч), Takashi Sakamoto (Зохиогч), Tsugumasa Toma (Зохиогч), Masaharu Sakamoto (Зохиогч), Mohammed A. S. Abourehab (Зохиогч), Masami Otsuka (Зохиогч), Mikako Fujita (Зохиогч), Hiroshi Tateishi (Зохиогч), Mohamed O. Radwan (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different bio-pertinent activities, especially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin a...