New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia

• Main Authors: Ahmed K. Hamdy (Author), Takashi Sakamoto (Author), Tsugumasa Toma (Author), Masaharu Sakamoto (Author), Mohammed A. S. Abourehab (Author), Masami Otsuka (Author), Mikako Fujita (Author), Hiroshi Tateishi (Author), Mohamed O. Radwan (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different bio-pertinent activities, especially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin a...