New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia
Searching for bioactive compounds within the huge chemical space is like trying to find a needle in a haystack. Isatin is a unique natural compound which is endowed with different bio-pertinent activities, especially in cancer therapy. Herein, we envisaged that adopting a hybrid strategy of isatin a...
Saved in:
Main Authors: | Ahmed K. Hamdy (Author), Takashi Sakamoto (Author), Tsugumasa Toma (Author), Masaharu Sakamoto (Author), Mohammed A. S. Abourehab (Author), Masami Otsuka (Author), Mikako Fujita (Author), Hiroshi Tateishi (Author), Mohamed O. Radwan (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Discovery of Azaindolin-2-One as a Dual Inhibitor of GSK3β and Tau Aggregation with Potential Neuroprotective Activity
by: Taha F. S. Ali, et al.
Published: (2022) -
Oxidative Stress and Chronic Myeloid Leukemia: A Balance between ROS-Mediated Pro- and Anti-Apoptotic Effects of Tyrosine Kinase Inhibitors
by: Alessandro Allegra, et al.
Published: (2024) -
The Anticancer Effects of the Pro-Apoptotic Benzofuran-Isatin Conjugate (5a) Are Associated With p53 Upregulation and Enhancement of Conventional Chemotherapeutic Drug Efficiency in Colorectal Cancer Cell Lines
by: Mansoor-Ali, et al.
Published: (2022) -
<i>In Vitro</i> Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with <i>In Silico</i> Insights
by: Halilibrahim Ciftci, et al.
Published: (2022) -
Identification of New L-Heptanoylphosphatidyl Inositol Pentakisphosphate Derivatives Targeting the Interaction with HIV-1 Gag by Molecular Modelling Studies
by: Halilibrahim Ciftci, et al.
Published: (2022)