Epigenetic changes associated with disease progression in a mouse model of childhood allergic asthma

• 主要な著者: Adam Collison (著者), Jessica S. Siegle (著者), Nicole G. Hansbro (著者), Chau-To Kwok (著者), Cristan Herbert (著者), Joerg Mattes (著者), Megan Hitchins (著者), Paul S. Foster (著者), Rakesh K. Kumar (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2013-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

SUMMARY Development of asthma in childhood is linked to viral infections of the lower respiratory tract in early life, with subsequent chronic exposure to allergens. Progression to persistent asthma is associated with a Th2-biased immunological response and structural remodelling of the airways. The...