Association of Immune and Metabolic Receptors C5aR and C5L2 with Adiposity in Women

• Main Authors: Pegah Poursharifi (Author), Reza Rezvani (Author), Abhishek Gupta (Author), Marc Lapointe (Author), Picard Marceau (Author), André Tchernof (Author), Katherine Cianflone (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adipose tissue receptors C5aR and C5L2 and their heterodimerization/functionality and interaction with ligands C5a and acylation stimulating protein (ASP) have been evaluated in cell and rodent studies. Their contribution to obesity factors in humans remains unclear. We hypothesized that C5a recepto...