A Randomized, Double-Blind, Single-Dose Study Comparing the Biosimilarity of HOT-1010 With Bevacizumab (Avastin®) in Chinese Healthy Male Subjects

• Main Authors: Kai Huang (Author), Linling Que (Author), Ying Ding (Author), Nannan Chu (Author), Zhenzhong Qian (Author), Yunfei Shi (Author), Wei Qin (Author), Zhenni Li (Author), Yuanxin Chen (Author), Xianghong Gu (Author), Jiakun Wang (Author), Lin Zhang (Author), Jisheng Zhang (Author), Xiangyang Zhu (Author), Yongmin Yang (Author), Yuan Tang (Author), Qing He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study was conducted to compare the pharmacokinetics, safety and immunogenicity of HOT-1010 with bevacizumab (Avastin®) in Chinese healthy male subjects.Methods: A single-center, randomized, double-blind, single-dose, parallel trial was performed in 84 Chinese healthy male subjects wh...