Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity

• Main Authors: Soo-Yeon Kim (Author), Whi-An Kwon (Author), Seung-Pil Shin (Author), Ho Kyung Seo (Author), Soo-Jeong Lim (Author), Yuh-Seog Jung (Author), Hyo-Kyung Han (Author), Kyung-Chae Jeong (Author), Sang-Jin Lee (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In a previous report, 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay) improved adenovirus transduction efficiency by shielding the negative surface charges of adenovirus particles. The present study analyzed the physicochemical characterization of the electrostatic complex of adeno...