Interfering with the AKT/mTOR/STAT3/ID1 signaling axis with usenamine A restrains the proliferative and invasive potential of human hepatocellular carcinoma cells

• Main Authors: Ailin Yang (Author), Huiming Huang (Author), Jinxin Xie (Author), Yingying Tian (Author), Longyan Wang (Author), Dongxiao Liu (Author), Xuejiao Wei (Author), Peng Tan (Author), Xingyun Chai (Author), Xiaojun Zha (Author), Pengfei Tu (Author), Zhongdong Hu (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Usenamine A, a novel natural compound initially isolated from the lichen Usnea longissima, has exhibited promising efficacy against hepatoma in prior investigation. Nevertheless, the underlying mechanisms responsible for its antihepatoma effects remain unclear. Furthermore, the r...