Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer

• Main Authors: Kudelaidi Kuerban (Author), Xiwen Gao (Author), Hui Zhang (Author), Jiayang Liu (Author), Mengxue Dong (Author), Lina Wu (Author), Ruihong Ye (Author), Meiqing Feng (Author), Li Ye (Author)
• Format: Book
• Published: Elsevier, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

More efficient drug delivery system and formulation with less adverse effects are needed for the clinical application of broad-spectrum antineoplastic agent doxorubicin (DOX). Here we obtained outer-membrane vesicles (OMVs), a nano-sized proteoliposomes naturally released by Gram-negative bacteria,...