Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer

• Autori principali: Kudelaidi Kuerban (Autore), Xiwen Gao (Autore), Hui Zhang (Autore), Jiayang Liu (Autore), Mengxue Dong (Autore), Lina Wu (Autore), Ruihong Ye (Autore), Meiqing Feng (Autore), Li Ye (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2020-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

More efficient drug delivery system and formulation with less adverse effects are needed for the clinical application of broad-spectrum antineoplastic agent doxorubicin (DOX). Here we obtained outer-membrane vesicles (OMVs), a nano-sized proteoliposomes naturally released by Gram-negative bacteria,...