The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a+/− Mouse Model of Dravet Syndrome

• Egile Nagusiak: Vaishali Satpute Janve (Egilea), Lyndsey L. Anderson (Egilea), Dilara Bahceci (Egilea), Nicole A. Hawkins (Egilea), Jennifer A. Kearney (Egilea), Jonathon C. Arnold (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Cannabidiol has been approved for the treatment of drug-resistant childhood epilepsies including Dravet syndrome (DS). Although the mechanism of anticonvulsant action of cannabidiol is unknown, emerging data suggests involvement of the transient receptor potential cation channel subfamily V member 1...