TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling

• Main Authors: Nigel Beaton (Author), Carla Rudigier (Author), Hansjörg Moest (Author), Sebastian Müller (Author), Nadja Mrosek (Author), Eva Röder (Author), Gottfried Rudofsky (Author), Thomas Rülicke (Author), Jozef Ukropec (Author), Barbara Ukropcova (Author), Robert Augustin (Author), Heike Neubauer (Author), Christian Wolfrum (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Failure to properly dispose of glucose in response to insulin is a serious health problem, occurring during obesity and is associated with type 2 diabetes development. Insulin-stimulated glucose uptake is facilitated by the translocation and plasma membrane fusion of vesicles containing g...