Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes.

• Main Authors: Monica Poggianella (Author), José L Slon Campos (Author), Kuan Rong Chan (Author), Hwee Cheng Tan (Author), Marco Bestagno (Author), Eng Eong Ooi (Author), Oscar R Burrone (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) infection is a major emerging disease widely distributed throughout the tropical and subtropical regions of the world affecting several millions of people. Despite constants efforts, no specific treatment or effective vaccine is yet available. Here we show a novel design of a DNA...