PBPK Modelling of Dexamethasone in Patients With COVID-19 and Liver Disease
The aim of the study was to apply Physiologically-Based Pharmacokinetic (PBPK) modelling to predict the effect of liver disease (LD) on the pharmacokinetics (PK) of dexamethasone (DEX) in the treatment of COVID-19. A whole-body PBPK model was created to simulate 100 adult individuals aged 18-60 year...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2022-01-01T00:00:00Z.
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