Suppression of CD13 Enhances the Cytotoxic Effect of Chemotherapeutic Drugs in Hepatocellular Carcinoma Cells

• Main Authors: Shengping Ji (Author), Yuqian Ma (Author), Xiaoyan Xing (Author), Binbin Ge (Author), Yutian Li (Author), Xinyue Xu (Author), Jiliang Song (Author), Mei Xiao (Author), Feng Gao (Author), Wenyan Jiang (Author), Chunyan Fang (Author), Xuejian Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) of hepatocellular carcinoma (HCC) is a serious problem that directly hinders the effect of chemotherapeutics. In this study, we mainly explore the molecular mechanism of ROS-induced CD13 expression using hepatocarcinoma cells as the research object. We show that the drug o...