A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis

• Main Authors: Mascarenhas Cláudia (Author), Krikler Samuel H (Author), Whittington Chris (Author), Cruz Eugénia (Author), Lacerda Rosa (Author), Vieira Jorge (Author), Porto Graça (Author)
• Format: Book
• Published: BMC, 2008-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hereditary Hemochromatosis(HH) is a common genetic disorder of iron overload where the large majority of patients are homozygous for one ancestral mutation in the <it>HFE </it>gene. In spite of this remarkable genetic hom...