Efficacy and Safety of Trametinib in Neurofibromatosis Type 1-Associated Plexiform Neurofibroma and Low-Grade Glioma: A Systematic Review and Meta-Analysis

• Main Authors: Dun Wang (Author), Lingling Ge (Author), Zizhen Guo (Author), Yuehua Li (Author), Beiyao Zhu (Author), Wei Wang (Author), Chengjiang Wei (Author), Qingfeng Li (Author), Zhichao Wang (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trametinib has been used in neurofibromatosis type 1 (NF1) patients, especially those with unresectable nerve tumors, but no systematic review based on the latest studies has been published. We conducted this meta-analysis to evaluate the effectiveness and safety of trametinib in treating NF1-relate...