Computational insights into the stereo-selectivity of catechins for the inhibition of the cancer therapeutic target EGFR kinase

• Main Authors: Mohd Rehan (Author), Firoz Ahmed (Author), Mohammad Imran Khan (Author), Hifzur Rahman Ansari (Author), Shazi Shakil (Author), Moustafa E. El-Araby (Author), Salman Hosawi (Author), Mohammad Saleem (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The epidermal growth factor receptor (EGFR) plays a crucial role in regulating cellular growth and survival, and its dysregulation is implicated in various cancers, making it a prime target for cancer therapy. Natural compounds known as catechins have garnered attention as promising anticancer agent...