Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis

• Main Authors: Nusaiba K. Al-Nemrawi (Author), Nid''A H. Alshraiedeh (Author), Aref L. Zayed (Author), Bashar M. Altaani (Author)
• Formato: Libro
• Publicado: MDPI AG, 2018-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

(1) Background: Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with Tobramycin were prepared using a solvent-evaporation method. (2) Methods: The NPs were coated with low molecular weight chitosan (LMWC) to enhance the mucoadhesiveness of PLGA-NPs. The following w/w ratios of tobram...