Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts

• 主要な著者: Terence Davis (著者), Amy J. C. Brook (著者), Michal J. Rokicki (著者), Mark C. Bagley (著者), David Kipling (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2016-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Progeroid syndromes show features of accelerated ageing and are used as models for human ageing, of which Werner syndrome (WS) is one of the most widely studied. WS fibroblasts show accelerated senescence that may result from p38 MAP kinase activation since it is prevented by the p38 inhibitor SB203...