A Novel Model of Pain Sensation Using Superfused Gastrosplenic Omentum Preparation of Anesthetized Rats

A pain model for screening analgesics was established in anesthetized rats. The omenta of urethane-anesthetized rats were exteriorized, fixed in a plastic chamber, and superfused with Tyrode solution. Administration of bradykinin (BK) in the chamber elicited the reflex hypertensive response (RHR). M...

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Main Authors: Shi-Jie Yang (Author), Makoto Katori (Author), Masataka Majima (Author)
Format: Book
Published: Elsevier, 2008-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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