PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway

• Päätekijät: Dool-Ri Oh (Tekijä), Hu Won Kang (Tekijä), Jong-Ro Kim (Tekijä), Sunoh Kim (Tekijä), In-Kyu Park (Tekijä), Joon Haeng Rhee (Tekijä), Won Keun Oh (Tekijä), Young Ran Kim (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2014-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Toll-like receptor (TLR) ligands are being developed for use as vaccine adjuvants and as immunomodulators because of their ability to stimulate innate and adaptive immune responses. Flagellin, a TLR5 ligand, was reported to show potent mucosal vaccine adjuvant activity. To identify ligands that pote...