PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway

• Principais autores: Dool-Ri Oh (Autor), Hu Won Kang (Autor), Jong-Ro Kim (Autor), Sunoh Kim (Autor), In-Kyu Park (Autor), Joon Haeng Rhee (Autor), Won Keun Oh (Autor), Young Ran Kim (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2014-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Toll-like receptor (TLR) ligands are being developed for use as vaccine adjuvants and as immunomodulators because of their ability to stimulate innate and adaptive immune responses. Flagellin, a TLR5 ligand, was reported to show potent mucosal vaccine adjuvant activity. To identify ligands that pote...