A novel heterologous receptor-binding domain dodecamer universal mRNA vaccine against SARS-CoV-2 variants

• Main Authors: Shugang Qin (Author), Hai Huang (Author), Wen Xiao (Author), Kepan Chen (Author), Xi He (Author), Xiaoshan Tang (Author), Zhiying Huang (Author), Yupei Zhang (Author), Xing Duan (Author), Na Fan (Author), Qian Zheng (Author), Min Wu (Author), Guangwen Lu (Author), Yuquan Wei (Author), Xiawei Wei (Author), Xiangrong Song (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There are currently approximately 4000 mutations in the SARS-CoV-2 S protein gene and emerging SARS-CoV-2 variants continue to spread rapidly worldwide. Universal vaccines with high efficacy and safety urgently need to be developed to prevent SARS-CoV-2 variants pandemic. Here, we described a novel...