Clinical and mutational profile of AT-rich interaction domain 1A-mutated cancers

• Main Authors: Rosa Falcone (Author), Marco Filetti (Author), Pasquale Lombardi (Author), Valeria Altamura (Author), Francesco Paroni Sterbini (Author), Giovanni Scambia (Author), Gennaro Daniele (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: AT-rich interaction domain 1A (ARID1A) encodes a key component of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex that participates in gene expression. ARID1A alterations are quite common among cancer patients, although their role remains debated. The aim of this artic...