Higher frequencies of circulating ICOS+, IL-21+ T follicular helper cells and plasma cells in patients with new-onset membranous nephropathy

• Main Authors: Zhihui Zhang (Author), Yunpeng Shi (Author), Kunmeng Yang (Author), Rebecca Crew (Author), Haifeng Wang (Author), Yanfang Jiang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: T follicular helper (TFH) cells and B cells are known to regulate humoral immune responses. This study is aimed at examining the putative contribution of different subsets of circulating of TFH cells and B cells to membranous nephropathy (MN). Methods: A total of 45 MN patients and 19 he...