MiR-486-5p Targets CD133+ Lung Cancer Stem Cells through the p85/AKT Pathway

• Main Authors: Massimo Moro (Author), Orazio Fortunato (Author), Giulia Bertolini (Author), Mavis Mensah (Author), Cristina Borzi (Author), Giovanni Centonze (Author), Francesca Andriani (Author), Daniela Di Paolo (Author), Patrizia Perri (Author), Mirco Ponzoni (Author), Ugo Pastorino (Author), Gabriella Sozzi (Author), Mattia Boeri (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite improvements in therapies and screening strategies, lung cancer prognosis still remains dismal, especially for metastatic tumors. Cancer stem cells (CSCs) are endowed with properties such as chemoresistance, dissemination, and stem-like features, that make them one of the main causes of the...