De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells.

• Main Authors: Douglas P Jasmer (Author), Bruce A Rosa (Author), Rahul Tyagi (Author), Christina A Bulman (Author), Brenda Beerntsen (Author), Joseph F Urban (Author), Judy Sakanari (Author), Makedonka Mitreva (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Efforts to identify new drugs for therapeutic and preventive treatments against parasitic nematodes have gained increasing interest with expanding pathogen omics databases and drug databases from which new anthelmintic compounds might be identified. Here, a novel approach focused on integrating a pa...