IL-1β and IL-6 modulate apolipoprotein E gene expression in rat hepatocyte primary culture

• Váldodahkkit: Agnes Ribeiro (Dahkki), Marise Mangeney (Dahkki), Isabelle Bernard (Dahkki), Jean Chambaz (Dahkki), Francisco Delers (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 1992-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Incubation of rat hepatocytes in primary culture with IL-1β at a concentration of 2.5 units/ml resulted in an increase (+80%) in the amount of apoE mRNA without any effect upon apoE synthesis. IL-6 at a low concentration (10 units/ml) induced a decrease (−35%) in the amount of apoE mRNA, but increas...