Liraglutide attenuates obese-associated breast cancer cell proliferation via inhibiting PI3K/Akt/mTOR signaling pathway

• Prif Awduron: Alaa Alanteet (Awdur), Hala Attia (Awdur), Musaed Alfayez (Awdur), Amer Mahmood (Awdur), Khalid Alsaleh (Awdur), Sary Alsanea (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2024-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

This study aims to explore the anti-proliferative, pro-apoptotic, and anti-migration activities of liraglutide (LGT) in MCF-7 breast cancer (BC) cells in subjects with obesity, particularly its effects on the PI3K/Akt/mTOR/AMPK pathway. The role of AMPK/SIRT-1, an essential regulator of adipokine pr...