Pioglitazone treatment mitigates cardiovascular bioprosthetic degeneration in a chronic kidney disease model

• Main Authors: Shintaro Katahira (Author), Mareike Barth (Author), Robin Döpp (Author), Yukiharu Sugimura (Author), Vera Schmidt (Author), Jessica Isabel Selig (Author), Yoshikatsu Saiki (Author), Joachim Jankowski (Author), Nikolaus Marx (Author), Willi Jahnen-Dechent (Author), Artur Lichtenberg (Author), Payam Akhyari (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AimsChronic kidney disease (CKD) is a risk factor for the development of cardiovascular diseases, e.g., atherosclerosis and calcific aortic valve disease, leading inevitably to valve replacement surgery. CKD patients with bioprosthetic cardiovascular grafts, in turn, have a higher risk of premature...