The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods

• Main Authors: Jan Chrz (Author), Markéta Dvořáková (Author), Kristina Kejlová (Author), Danuše Očadlíková (Author), Lada Svobodová (Author), Lukáš Malina (Author), Barbora Hošíková (Author), Dagmar Jírová (Author), Hana Bendová (Author), Hana Kolářová (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triclosan and Triclocarban, preservatives widely used in cosmetics and other consumer products, underwent evaluation using a battery of new-approach methodologies in vitro (NAMs). Specifically, the Microplate Ames Test (MPF™ Test, Xenometrix, Allschwil, Switzerland) was employed to assess mutagenici...