Floroquinone induces apoptosis and inhibits carcinoma growth in mouse tumor xenograft model of anaplastic thyroid cancer

• Главные авторы: Li-Na Zhao (Автор), Li-Bo Chen (Автор), Xiu-Hua Hao (Автор), Zhang Hu (Автор), Jing Zhang (Автор), Chun-Hai Zhang (Автор)
• Формат: ‌
• Опубликовано: Bangladesh Pharmacological Society, 2016-07-01T00:00:00Z.
• Предметы: article
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In the present study, effects of floroquinone on anaplastic thyroid cancer cell lines and mouse tumor xenografts were investigated. Increase in the concentration of floroquinone from 10 to 100 µM reduced the cell growth from 98 to 17% after 48 hours in HOTHC cells. Similarly, in FRO cells growth rat...