Nanoparticles Carrying NF-κB p65-Specific siRNA Alleviate Colitis in Mice by Attenuating NF-κB-Related Protein Expression and Pro-Inflammatory Cellular Mediator Secretion

Ulcerative colitis is a disease that causes inflammation and ulcers in the colon and which is typically recurrent, and NF-κB proteins are important players during disease progression. Here, we assess the impact of silica-coated calcium phosphate nanoparticles carrying encapsulated siRNA against NF-κ...

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Main Authors: Elena K. Müller (Author), Nataniel Białas (Author), Matthias Epple (Author), Ingrid Hilger (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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