Nanoparticles Carrying NF-κB p65-Specific siRNA Alleviate Colitis in Mice by Attenuating NF-κB-Related Protein Expression and Pro-Inflammatory Cellular Mediator Secretion

• मुख्य लेखकों: Elena K. Müller (लेखक), Nataniel Białas (लेखक), Matthias Epple (लेखक), Ingrid Hilger (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Ulcerative colitis is a disease that causes inflammation and ulcers in the colon and which is typically recurrent, and NF-κB proteins are important players during disease progression. Here, we assess the impact of silica-coated calcium phosphate nanoparticles carrying encapsulated siRNA against NF-κ...