Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115

Abstract Background L-asparaginase is a potential therapeutic enzyme widely used in the chemotherapy protocols of pediatric and adult patients with acute lymphoblastic leukemia. However, its use has been limited by a high rate of hypersensitivity in the long-term used. Hence, there is a continuing n...

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Päätekijät: Noura El-Ahm (Tekijä), Sahar F. Deraz (Tekijä), Sara M. El-Ewasy (Tekijä), Ghada M. Suddek (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: BMC, 2018-08-01T00:00:00Z.
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