A meta-analysis and systematic review of the prevalence of mitochondrially encoded 12S RNA in the general population: Is there a role for screening neonates requiring aminoglycosides?

• Автори: Titus S Ibekwe (Автор), Sanjiv K Bhimrao (Автор), Brian D Westerberg (Автор), Frederick K Kozak (Автор)
• Формат: Книга
• Опубліковано: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: This was a meta-analysis and systematic review to determine the global prevalence of the mitochondrially encoded 12S RNA (MT-RNR1) genetic mutation in order to assess the need for neonatal screening prior to aminoglycoside therapy. Materials and Methods: A comprehensive search of MEDLINE...