Exposure-Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer

• मुख्य लेखकों: Thomas Rodier (लेखक), Alicja Puszkiel (लेखक), Evelina Cardoso (लेखक), David Balakirouchenane (लेखक), Céline Narjoz (लेखक), Jennifer Arrondeau (लेखक), Vincent Fallet (लेखक), Nihel Khoudour (लेखक), Monia Guidi (लेखक), Michel Vidal (लेखक), Xavier Declèves (लेखक), Chantal Csajka (लेखक), Jérôme Alexandre (लेखक), Jacques Cadranel (लेखक), Elizabeth Fabre (लेखक), Marie Wislez (लेखक), François Goldwasser (लेखक), Benoit Blanchet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

High interindividual variability (IIV) of the clinical response to epidermal growth factor receptor (EGFR) inhibitors such as osimertinib in non-small-cell lung cancer (NSCLC) might be related to the IIV in plasma exposure. The aim of this study was to evaluate the exposure-response relationship for...