FMR1 allelic complexity in premutation carriers provides no evidence for a correlation with age at amenorrhea

• Автори: Bárbara Rodrigues (Автор), Vanessa Sousa (Автор), Carolyn M. Yrigollen (Автор), Flora Tassone (Автор), Olatz Villate (Автор), Emily G. Allen (Автор), Anne Glicksman (Автор), Nicole Tortora (Автор), Sarah L. Nolin (Автор), António J. A. Nogueira (Автор), Paula Jorge (Автор)
• Формат: Книга
• Опубліковано: BMC, 2024-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Premutations in the Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene, defined as between 55 and 200 CGGs, have been implicated in fragile X-associated primary ovarian insufficiency (FXPOI). Only 20% of female premutation carriers develop early ovulatory dysfunction, the reason...