Population Pharmacokinetics of Lithium in Young Pediatric Patients With Intellectual Disability

• Main Authors: Junying Yuan (Author), Bohao Zhang (Author), Yiran Xu (Author), Xiaoli Zhang (Author), Juan Song (Author), Wenhao Zhou (Author), Kai Hu (Author), Dengna Zhu (Author), Lirong Zhang (Author), Fengmin Shao (Author), Shusheng Zhang (Author), Junjie Ding (Author), Changlian Zhu (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Lithium is a well-established treatment for bipolar disorders and has been shown to be neuroprotective, and thus low doses might be useful for the treatment of childhood brain injury and neurological sequelae. However, pharmacokinetic (PK) data in children are limited. This study was to...