Cyclodextrine Screening for the Chiral Separation of Amlodipine Enantiomers by Capillary Electrophoresis

• Autori principali: Gabriel Hancu (Autore), Monica Budău (Autore), Lajos Kristóf Kántor (Autore), Anca Cârje (Autore)
• Natura: Libro
• Pubblicazione: Tabriz University of Medical Sciences, 2015-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Purpose: Amlodipine is a long acting, dihydropyridine type calcium channel blocker frequently used in the treatment of hypertension and coronary insufficiency. The calcium channel blocking activity resides primarily in the S-amlodipine enantiomer, while R-amlodipine is a potent inhibitor of smooth m...