Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS. In particular, levels of ceramides, glucosylceramides, and gangliosides are dysregulated in the central nervous system and at...

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Main Authors: Alexandra Bouscary (Author), Cyril Quessada (Author), Althéa Mosbach (Author), Noëlle Callizot (Author), Michael Spedding (Author), Jean-Philippe Loeffler (Author), Alexandre Henriques (Author)
Format: Book
Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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