Maprotiline inhibits LPS-induced expression of adhesion molecules (ICAM-1 and VCAM-1) in human endothelial cells

• Main Authors: Laleh Rafiee (Author), Valiollah Hajhashemi (Author), Shaghayegh Haghjooy Javanmard (Author)
• Format: Knjiga
• Izdano: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Regardless of the known anti-inflammatory potential of heterocyclic antidepressants, the mechanisms concerning their modulating effects are not completely known. In our earlier work, maprotiline, a heterocyclic antidepressants, considerably inhibited infiltration of polymorphonuclear cell leucocytes...