Prediction of the active compounds and mechanism of Biochanin A in the treatment of Legg-Calvé-Perthes disease based on network pharmacology and molecular docking

• Hauptverfasser: Jianhong Liu (Verfasst von), Zhirui Hua (Verfasst von), Shijie Liao (Verfasst von), Boxiang Li (Verfasst von), Shengping Tang (Verfasst von), Qian Huang (Verfasst von), Zhendi Wei (Verfasst von), Rongbin Lu (Verfasst von), Chengsen Lin (Verfasst von), Xiaofei Ding (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Legg-Calvé-Perthes disease is a special self-limited disease in pediatric orthopedics with a high disability rate and a long-term course, and there is still no clear and effective therapeutic drug in clinic. This study aimed to investigate the potential efficacy of biochanin A, a...