Alleviating Effects of AS1892802, a Rho Kinase Inhibitor, on Osteoarthritic Disorders in Rodents

Alleviating Effects of AS1892802, a Rho Kinase Inhibitor, on Osteoarthritic Disorders in Rodents

The effects of AS1892802, a selective Rho-associated coiled coil kinase (ROCK) inhibitor, on knee cartilage damage and pain behavior were examined in a rat model of osteoarthritis (OA). Monoiodoacetate (MIA) was intraarticularly injected into the right knee joints of rats. ROCK I and II mRNA levels...

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Main Authors: Nobuaki Takeshita (Author), Eiji Yoshimi (Author), Chie Hatori (Author), Fumiyo Kumakura (Author), Nobuo Seki (Author), Yasuaki Shimizu (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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3rd Floor Main Library

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