Alleviating Effects of AS1892802, a Rho Kinase Inhibitor, on Osteoarthritic Disorders in Rodents
The effects of AS1892802, a selective Rho-associated coiled coil kinase (ROCK) inhibitor, on knee cartilage damage and pain behavior were examined in a rat model of osteoarthritis (OA). Monoiodoacetate (MIA) was intraarticularly injected into the right knee joints of rats. ROCK I and II mRNA levels...
Saved in:
Main Authors: | Nobuaki Takeshita (Author), Eiji Yoshimi (Author), Chie Hatori (Author), Fumiyo Kumakura (Author), Nobuo Seki (Author), Yasuaki Shimizu (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2011-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sustained Analgesic Effect of the Rho Kinase Inhibitor AS1892802 in Rat Models of Chronic Pain
by: Eiji Yoshimi, et al.
Published: (2010) -
The Role of Rho Kinase Inhibitors in Corneal Diseases
by: Futterknecht S, et al.
Published: (2024) -
Investigational Rho Kinase Inhibitors for the Treatment of Glaucoma
by: Al-Humimat G, et al.
Published: (2021) -
Mechanical stress regulates gene expression via Rho/Rho-kinase signaling pathway
by: Takako Kaneko-Kawano, et al.
Published: (2015) -
Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog
by: Bianca Lourdes FREHNER, et al.
Published: (2021)