Metabolic Profiles of New Unsymmetrical Bisacridine Antitumor Agents in Electrochemical and Enzymatic Noncellular Systems and in Tumor Cells

• Main Authors: Anna Mieszkowska (Author), Anna M. Nowicka (Author), Agata Kowalczyk (Author), Agnieszka Potęga (Author), Monika Pawłowska (Author), Michał Kosno (Author), Ewa Augustin (Author), Zofia Mazerska (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

New unsymmetrical bisacridines (UAs) demonstrated high activity not only against a set of tumor cell lines but also against human tumor xenografts in nude mice. Representative UA compounds, named C-2028, C-2045 and C-2053, were characterized in respect to their physicochemical properties and the fol...