Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms

• Main Authors: Yu Dong (Author), Xu-Xu Zhuang (Author), Yi-Ting Wang (Author), Jieqiong Tan (Author), Du Feng (Author), Min Li (Author), Qing Zhong (Author), Zhiyin Song (Author), Han-Ming Shen (Author), Evandro F. Fang (Author), Jia-Hong Lu (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Maintaining mitochondrial homeostasis is a potential therapeutic strategy for various diseases, including neurodegenerative diseases, cardiovascular diseases, metabolic disorders, and cancer. Selective degradation of mitochondria by autophagy (mitophagy) is a fundamental mitochondrial quality contro...