β-Cyclodextrin as a Functional Excipient Used for Enhancing the Diminazene Aceturate Bioavailability

• Asıl Yazarlar: Narcisa Marangoci (Yazar), Daniel Timpu (Yazar), Andreia Corciova (Yazar), Cornelia Mircea (Yazar), Anca-Roxana Petrovici (Yazar), Alina Nicolescu (Yazar), Elena-Laura Ursu (Yazar), Valentin Nastasa (Yazar), Andra-Cristina Bostanaru (Yazar), Mihai Mares (Yazar), Mihaela Pertea (Yazar), Mariana Pinteala (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2019-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In this study, we proposed formulations of diminazene aceturate (DA) designed to improve its bioavailability and to maximize the therapeutic index in animals by overcoming the rapid degradation under the acidic pH of the stomach. An important consequence is the fact that its amount in the bloodstrea...