Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells

• المؤلفون الرئيسيون: Sarah Tauber (مؤلف), Maria Katharina Sieckmann (مؤلف), Katrin Erler (مؤلف), Wilhelm Stahl (مؤلف), Lars-Oliver Klotz (مؤلف), Holger Steinbrenner (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Selenoenzymes, whose activity depends on adequate selenium (Se) supply, and phase II enzymes, encoded by target genes of nuclear factor erythroid 2-related factor 2 (Nrf2), take part in governing cellular redox homeostasis. Their interplay is still not entirely understood. Here, we exposed HepG2 hep...