Potential tactics with vitamin D and certain phytochemicals for enhancing the effectiveness of immune-checkpoint blockade therapies

• Main Authors: Ai Tsuji (Author), Sayuri Yoshikawa (Author), Sae Morikawa (Author), Yuka Ikeda (Author), Kurumi Taniguchi (Author), Haruka Sawamura (Author), Tomoko Asai (Author), Satoru Matsuda (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunotherapy strategies targeting immune checkpoint molecules such as programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) are revolutionizing oncology. However, its effectiveness is limited in part due to the loss of effector cytotoxic T lymphocytes. Interestingl...