Dual Targeting of Cancer Cells and MMPs with Self-Assembly Hybrid Nanoparticles for Combination Therapy in Combating Cancer

• Main Authors: Kai Zhang (Author), Jingjing Li (Author), Xiaofei Xin (Author), Xiaoqing Du (Author), Di Zhao (Author), Chao Qin (Author), Xiaopeng Han (Author), Meirong Huo (Author), Lei Yang (Author), Lifang Yin (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The co-delivery of chemotherapeutic agents and immune modulators to their targets remains to be a great challenge for nanocarriers. Here, we developed a hybrid thermosensitive nanoparticle (TMNP) which could co-deliver paclitaxel-loaded transferrin (PTX@TF) and marimastat-loaded thermosensitive lipo...